Simultaneous Determination of Chlorthalidone and Spironolactone with Univariate and Multivariate Calibration: Wavelength Range Selection
نویسندگان
چکیده
منابع مشابه
Simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate Calibration Methods
Two multivariate calibration methods are compared for the simultaneous chromatographic determination and separation of Sulfamethoxazole (SMX) and Phthalazine (PHZ) by High Performance Liquid Chromatography (HPLC). Multivariate calibration techniques such as Classical Least Squares (CLS) and Inverse Least Squares (ILS) were introduced into HPLC to determine the quantification by using UV d...
متن کاملWavelength region selection and spectrophotometric simultaneous determination of naphthol isomers based on net analyte signal
Naphthol isomers were simultaneously and spectrophotometrically determined in wastewater, using a model based on net analyte signal (NAS). The calibration method used is a variation of the original hybrid linear analysis method as proposed by Goicoechea and Olivieri (HLA/GO). Owing to spectral interferences, the simultaneous determination of mixtures of naphthol isomers, using a spectrophotomet...
متن کاملSimultaneous spectrophotometric determination of ampicillin and penicillin in human plasma using multivariate calibration
An analytical methodology based on spectrophotometric and partial least squares (PLS) algorithm for thesimultaneous determination of ampicillin and penicillin in human plasma was developed and validated. Themultivariate model was developed as a binary calibration model and it was built and validated with anindependent set of synthesis and real samples in presence of matrix. It is shown how a de...
متن کاملSimultaneous spectrophotometric determination of lidocaine and hydrocortisone acetate in pharmaceutical preparations by multivariate calibration methods
The multivariate calibration method, partial least square regression (PLS) was applied for thesimultaneous spectrophotometric determination of Lidocaine (LID) and Hydrocortisone acetate(HCA) in their mixtures. The parameters of chemometric technique were optimized and theproposed method was validated with synthetic samples and applied to analyze these drugs inpharmaceutical products with good a...
متن کاملsimultaneous spectrophotometric determination of amlodipine and metoprolol by principal componentregression multivariate calibration and comparison with hplc
multi-drug therapy in high blood pressure is appreciated to achieve a normalblood pressure.a simple spectrophotometric method based on principal component analysis has been proposed for simultaneous determination of amlodipine (amd) and metoprolol(met) in pharmacutical preparations. calibration matrix contains 3.402 µgml -1 to 170.130 µgml -1 and from 13.060 µgml -1 to 65.3 µgml -1 amlodipine a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of AOAC INTERNATIONAL
سال: 1999
ISSN: 1060-3271,1944-7922
DOI: 10.1093/jaoac/82.5.1054